Highly selective first generation glucose biosensor based on carbon paste containing copper and glucose oxidase

MARCELA C. RODRIGUEZ; GUSTAVO A. RIVAS

ELECTROANALYSIS

Wiley Interscience

Lugar: Weinheim; Año: 2001 vol. 13 p. 1179 - 1179

1040-0397

span lang="en" style="FONT-SIZE: 10pt; FONT-FAMILY: Arial; mso-ansi-language: EN-US"> A highly selective electrochemical glucose biosensor based on the dispersion of copper microparticles and glucose oxidase into a carbon paste matrix is described. Copper offers a very efficient and preferential electrocatalytic activity towards the reduction of enzymatically generated hydrogen peroxide. Careful evaluation of the influence of copper content in the paste on the sensitivity and selectivity of the biosensor was performed, and 1.2% w/w copper was selected as the optimum. Hence, the strong electrocatalytic effect of copper towards hydrogen peroxide allows for a fast and remarkably selective glucose quantification at -0.100V. No interference was observed even in the presence of large excess of ascorbic acid